Inhibiting Doxorubicin-Induced Cardiotoxicity
Study finds Sodium Thiosulfate reduces Doxorubicin (DOX)-induced DNA damage Doxorubicin (DOX), commonly used to treat a variety of cancers, has...
Advances in Non-Invasive Hormone Monitoring
Corticosterone & Non-Invasive Sample Types Corticosterone—the most common glucocorticoid in rodent animal models of stress—is easily measured using ELISA techniques....
Dietary Antioxidants: Using Diets to Reduce Stress
Reactive Oxygen Species (ROS) can react with vital macromolecules, damaging biomolecules critical to cellular structure and function. Antioxidants protect biological...
Salivary Cortisol: Detecting Stress in Critical Incident Training
The negative impact stress has on health and performance is well documented. Consequently, stress assessment and mitigation strategies are the...
Novel Tools for Reproductive Biology
Novel Tools for Reproductive Biology Cell-based models are indispensable tools in the study of embryology and reproductive biology. However, the...
Oxidative Stress, Copper, and Glutathione
Regulation of Copper Transport and Cell Viability During Copper Metabolism Copper (Cu) is an essential cofactor in virtually all organisms,...
Simplify Your Glutathione Measurements
Glutathione, the major endogenous antioxidant produced by cells, plays a critical role in protecting organisms from oxidative stress and related cytotoxicity....
Glutathione—Mediator of Oxidative Stress
Stress at the Cellular Level Cells maintain an equilibrium of molecular oxygen and various antioxidants. An imbalance of reactive oxygen...
STING Agonist cGAMP Is a Potent Vaccine Adjuvant
We know the cGAS–STING pathway is a key activator of the innate immune response to cellular damage or microbial infection. Cyclic GMP-AMP...
What Makes Cortisol Different Among Species?
STUMPED? The molecules, of course, are 100% identical. The structure of the cortisol molecule is exactly the same regardless of...
Neonatal Stress Alters Adult Behavior and Stress Reactivity
Early-life stressful experiences can have negative consequences on brain maturation. To understand the long-term implications of neonatal stress, researchers from...
3′,3′-Cyclic GAMP Assay: The Newest Tool in the Researcher’s Arsenal
Cyclic dinucleotides are the most abundant second messengers in bacteria, modulating a variety of cellular activities in prokaryotic cells.  3’3’-cyclic GAMP...